GHRP-6 (5mg / 10mg)
$19.00 - $39.00
GHRP-6 Product Information
Our GHRP-6 is a high-purity, synthetic peptide available in both 5mg and 10mg sizes. Provided in a lyophilized powder form with a certified purity of >99%, it is intended for research purposes. The SKU is P-GHRP6.
Pricing and Discounts:
5-8 units: A 5% discount is applied, with prices ranging from $19.00 - $27.55.
9+ units: A 10% discount is applied, with prices ranging from $18.00 - $26.10.
We also offer FREE shipping on all orders over $200.
GHRP-6 (Growth Hormone Releasing Hexapeptide 6) is a synthetic peptide that is the subject of research for its potential to stimulate the secretion and regulation of growth hormone (GH). It is an analog of the neurotransmitter met-enkephalin but lacks opioid activity, instead interacting with growth hormone secretagogue receptors (GHS-Rs), which are also known as ghrelin receptors.
Key Research Areas 🔬
1. Growth Hormone Synthesis
GHRP-6 is being researched for its potential to stimulate GH release by acting on the hypothalamus and pituitary gland.
Mechanism: The peptide is believed to act on the hypothalamic-pituitary axis. Studies suggest that GHRP-6's action may be dependent on the presence of endogenous GHRH (Growth Hormone-Releasing Hormone). It is also posited that GHRP-6 may function as an antagonist to somatostatin, a hormone that inhibits GH secretion, thus allowing for increased GH release.
Studies: Research has shown that GHRP-6 may induce GH secretion at levels significantly higher than those achieved with GHRH alone. One study reported a GH peak of 15.4 μg/L after GHRP-6 exposure, compared to a physiological peak of 5.5 μg/L.
2. Appetite Regulation and Metabolism
Because GHRP-6 interacts with ghrelin receptors, it is being researched for its potential to influence appetite and metabolism.
Mechanism: Ghrelin is known as the "hunger hormone." By activating ghrelin receptors, GHRP-6 is hypothesized to influence various functions, including nutrient absorption and metabolism.
Studies: Research on GHRP-6 and its potential on organ function suggested that it may impact gut epithelial cells and increase cell migration. Additionally, a study on diabetic mice models suggested that the peptide improved gastric emptying (GE) and intestinal transit (IT), which are often delayed in diabetes.
3. Tissue Repair and Regeneration
GHRP-6 has been associated with tissue recovery and repair.
Organ Function: Studies on models of multiple organ failure suggested that GHRP-6 may reduce hepatic and intestinal damage and lipid peroxidation.
Wound Healing: Research in animal models suggested that GHRP-6 may contribute to faster wound healing and a reduction in hypertrophic scar development by lessening inflammation and the expression of fibrotic cytokines. A separate preclinical investigation on rats with burn injuries also suggested improved wound healing due to a reduction in pro-inflammatory agents.
Liver Fibrosis: A study suggested that prolonged exposure to GHRP-6 may potentially decrease liver fibrosis and reduce fibrogenic factors.
4. Neuroprotection
Some research suggests that GHRP-6 may have a protective effect on nerve tissue.
Mechanism: The potential benefits of GH, which GHRP-6 may stimulate, are often believed to be mediated via IGF-1 (insulin-like growth factor-1). Studies have shown that GHRP-6 may elevate IGF-1 mRNA levels in specific areas of the brain, such as the hypothalamus, cerebellum, and hippocampus.
Cellular Survival: Research also suggests that GHRP-6 may activate cellular survival pathways and increase the antiapoptotic protein Bcl-2, while leaving the proapoptotic protein Bax levels consistent, hinting at a shift towards cell preservation.
Product Specifications 📊
Molecular Formula: C46H56N12O6
Molecular Weight: 873.03 g/mol
Other Known Titles: Growth Hormone Releasing Peptide-6
Important Notice: GHRP-6 peptide is available for research and laboratory purposes only. It is not intended for human or veterinary use. All information provided is for educational and scientific reference only and has not been evaluated by the FDA or any medical regulatory body.