Ipamorelin (5mg)
$39.00 $23.00
Ipamorelin Product Information
Our Ipamorelin is a high-purity, synthetic peptide available in a 5mg size. Provided as a lyophilized powder with a certified purity of >99%, it is intended for research purposes. The SKU is P-IPAMORELIN-5.
Pricing and Discounts
5-8 units: A 5% discount is applied, with a price of $40.85 per unit.
9+ units: A 10% discount is applied, with a price of $38.70 per unit.
We also offer FREE shipping on all orders over $200.
Ipamorelin is a synthetic peptide, formally classified as a Growth Hormone Secretagogue (GHS), that is the subject of research for its potential to selectively trigger the release of growth hormone (GH) from the pituitary gland. It is composed of five amino acids and is thought to act by binding to and activating ghrelin receptors, which are also known as Growth Hormone Secretagogue receptors (GHS-Rs).
Mechanisms of Action and Research 🔬
1. Growth Hormone Synthesis
Ipamorelin's primary research focus is its potential to selectively stimulate the synthesis and release of GH.
Mechanism: The peptide is believed to act on somatotroph cells in the anterior pituitary gland, triggering a signaling cascade that involves the release of calcium ions and the activation of protein kinase C (PKC). This process is thought to culminate in the release of vesicles filled with growth hormones.
Selectivity: Studies suggest that Ipamorelin may be highly selective for GH release, and unlike some other GH-releasing peptides, it may not significantly affect the levels of other pituitary hormones such as prolactin or ACTH.
Studies: A clinical trial reported that Ipamorelin tended to boost GH levels, with one case showing an increase of over 60-fold compared to a placebo.
2. Bone Tissue
Ipamorelin has been researched for its potential to influence bone mineral density.
Mechanism: The peptide might stimulate osteoblasts (bone-forming cells) through GH-mediated pathways, potentially leading to their enhanced proliferation and growth.
Studies: A study on murine models suggested that Ipamorelin may increase body mass and elevate the overall bone mineral content (BMC) in the tibia and vertebrae. Additionally, an observed increase in the cross-sectional area of the bone was noted, indicating potential bone enlargement.
3. Digestion and Appetite
Ipamorelin is being explored for its potential effects on the digestive system and appetite.
Gastric Emptying: Research suggests that Ipamorelin may accelerate the process of gastric emptying, which is particularly interesting in models with delayed gastric emptying. It is thought to enhance the contractility of the stomach's smooth muscles.
Appetite: Due to its potential action on ghrelin receptors, Ipamorelin may lead to an enhancement in hunger signals. A study on research models suggested that Ipamorelin exposure was associated with a 15% surge in body weight and a proportional increase in fat pad weight.
4. Nitrogen Balance and Anabolism
Anabolic Action: Ipamorelin is being researched for its potential anabolic effects, which may be mediated through its potential to stimulate GH and IGF-1 synthesis.
Nitrogen Balance: A study on induced catabolic states suggested that Ipamorelin may have contributed to a 20% reduction in CUNS (a marker of liver's nitrogen processing) and appeared to restore nitrogen balance.
Product Specifications 📊
Molecular Formula: C38H49N9O5
Molecular Weight: 711.86 g/mol
Other Known Titles: NNC 26-0161
Important Notice: Ipamorelin peptide is available for research and laboratory purposes only. It is not intended for human or veterinary use. All information provided is for educational and scientific reference only and has not been evaluated by the FDA or any medical regulatory body.