KPV (4mg)
$35.00 $28.00
KPV Product Information
Our KPV is a high-purity, synthetic peptide available in a 4mg size. Provided as a lyophilized powder with a certified purity of >99%, it is intended for research purposes. The SKU is P-KPV-4.
Pricing and Discounts
5-8 units: A 5% discount is applied, with a price of $36.10 per unit.
9+ units: A 10% discount is applied, with a price of $34.20 per unit.
We also offer FREE shipping on all orders over $200.
KPV peptide is a synthetic tripeptide made of lysine, proline, and valine. It is a C-terminal fragment of the naturally occurring hormone alpha melanocyte-stimulating hormone (α-MSH) and is being researched for its potential anti-inflammatory properties and role in wound healing.
Key Research Areas 🔬
1. Anti-inflammatory Action
KPV is primarily researched for its potential to reduce inflammation.
Mechanism: The peptide's anti-inflammatory action may be induced by inactivating inflammatory pathways and inhibiting the synthesis and release of pro-inflammatory cytokines like TNF-α.
Intestinal Protection: Studies on murine models with intestinal inflammation suggested that KPV may reduce inflammatory cells and help protect the intestinal mucosa. The peptide's action in intestinal cells may involve the PepT1 transporter, which is thought to help deliver the peptide to the site of inflammation.
General Inflammation: An early study on mice with swollen ears suggested that KPV was as effective as the larger α-MSH molecule in reducing swelling. Another study reported that KPV may have antipyretic (fever-reducing) properties.
2. Wound Healing and Scar Formation
KPV is being explored for its potential to aid in the healing process and reduce scar formation.
Mechanism: KPV is an analog of α-MSH, which binds to the melanocortin 1 receptor (MC1R). Researchers hypothesize that KPV may also bind to these receptors, influencing the complex process of wound healing. Studies also suggest a potential link between KPV's healing properties and nitric oxide (NO) activity.
Wound Healing: Research on corneal epithelial wounds suggested that KPV may accelerate the healing process. In a study, all corneas exposed to KPV achieved complete re-epithelialization within 60 hours, compared to none in the placebo group.
Scar Formation: A study on murine models with surgical incisions found that KPV appeared to reduce inflammation in the early stages of healing and led to a smaller scar area compared to the control group in the later stages.
Product Specifications 📊
Molecular Formula: C16H30N4O4
Molecular Weight: 342.43 g/mol
Other Known Titles: MSH (11-13), ACTH(11-13), alpha-MSH(11-13)
Important Notice: KPV peptide is available for research and laboratory purposes only. It is not intended for human or veterinary use. All information provided is for educational and scientific reference only and has not been evaluated by the FDA or any medical regulatory body.