LL-37 10mg

Deepen your investigation into innate immunity and cellular signaling with LL-37. As the only member of the cathelicidin family identified in humans, LL-37 is a 37-amino acid, amphipathic alpha-helical peptide. It is a cornerstone for researchers studying the first line of defense against microbial pathogens and the complex orchestration of the inflammatory response.

Beyond its broad-spectrum antimicrobial properties, LL-37 is extensively researched for its role as a potent immunomodulator. In in vitro research models, it is utilized to explore pathways involving chemotaxis, wound healing, angiogenesis, and the neutralization of lipopolysaccharides (LPS). Our formulation is synthesized to achieve a high degree of purity, providing a stable, crystalline-lyophilized substrate for precise and reproducible experimental data.

Technical Specifications

• Compound: LL-37 (Human Cathelicidin Fragment)

• Unit Size: 10mg per vial

• Sequence: Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser

• Molecular Formula: $C_{205}H_{340}N_{60}O_{53}$

• Molecular Weight: ~4493.3 Da

• Form: Crystalline Lyophilized Peptide

• Solubility: Readily soluble in sterile water or compatible aqueous laboratory buffers.

Storage & Handling Protocols

To ensure the maximum biological activity and prevent peptide denaturation:

• Initial Storage: Store the lyophilized powder in a dry, sealed container under refrigeration between 2°C–8°C.

• Environmental Protection: Protect the material from moisture and direct UV light exposure to maintain molecular stability.

• Post-Reconstitution: Once in solution, the material must be kept refrigerated at 2°C–8°C. For optimal experimental fidelity, utilize the reconstituted material within your laboratory’s validated stability window.

Intended Use & Professional Compliance

For In Vitro Research Use Only.

This compound is intended strictly for in vitro laboratory research by qualified professionals or accredited institutions. It is not approved for human or animal administration. This material must not be incorporated into food, drugs, dietary supplements, cosmetics, or pharmaceutical products.

Legal Disclaimer:

This product and its associated technical data have not been evaluated by the U.S. Food and Drug Administration (FDA). No claims are made regarding the diagnosis, treatment, cure, or prevention of any disease. Use is strictly limited to qualified research professionals in certified laboratory environments.

Terms of Sale:

By purchasing from Mile High Compounds, the buyer affirms their status as a qualified researcher or representing a licensed institution. The purchaser assumes full and sole responsibility for the lawful handling, storage, and experimental application of this material in accordance with all local, state, and federal regulations. All sales are final.