Melanotan 1 (10mg)
$43.00 $25.00
Melanotan 1 Product Information
Our Melanotan 1 is a high-purity, synthetic peptide available in a 10mg size. Provided as a lyophilized powder with a certified purity of >99%, it is intended for research purposes. The SKU is P-MELANTN1-10.
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Melanotan 1 (MT1 or afamelanotide) is a synthetic peptide that is being researched for its potential to mimic the function of the natural alpha-melanocyte stimulating hormone (α-MSH). It is structurally similar to α-MSH but has been modified to potentially increase its affinity for target cells and extend its half-life.
Key Research Areas 🔬
1. Skin Pigmentation and UV Protection
Mechanism: Melanotan 1 is hypothesized to primarily act by binding to the melanocortin 1 receptor (MC1R), which is found on melanocytes (skin cells responsible for pigmentation). This interaction is believed to activate a signaling pathway that leads to the production of eumelanin, a photoprotective compound.
Studies: Research suggests that by promoting eumelanin production, Melanotan 1 may increase skin pigmentation, leading to a "tanned" appearance, and potentially enhance the skin's natural defense against UV radiation damage. Studies on erythropoietic porphyria models suggested that subjects exposed to the peptide were able to spend more time in sunlight with reduced pain. Clinical trials have also indicated a positive correlation between Melanotan 1 exposure and melanin production, as observed by relative tanning.
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2. Anti-inflammatory Action
Mechanism: Studies suggest that Melanotan 1 and other α-MSH analogs may have anti-inflammatory properties. This is believed to be achieved by modulating gene expression, particularly by downregulating pro-inflammatory and fibrogenic genes.
Studies: Research on murine models of liver fibrosis suggested that Melanotan 1 analogs might reverse established fibrosis and mitigate the upregulation of fibrogenic and pro-inflammatory gene expressions. They appeared to increase the activity of enzymes (MMPs) that degrade the extracellular matrix while decreasing the activity of markers associated with inflammation and fibrogenesis.
3. The Melanocortin System
Receptor Specificity: Melanotan 1 is being researched for its particular affinity towards MC1R. The peptide is also being explored for its potential interaction with other melanocortin receptors (MC2R-MC5R), each of which is associated with different biological processes like cortisol production, appetite regulation, and energy homeostasis.
Product Specifications 📊
Molecular Formula: C78H111N21O19
Molecular Weight: 1646.87 g/mol
Other Known Titles: MT1; afamelanotide
Important Notice: Melanotan 1 peptide is available for research and laboratory purposes only. It is not intended for human or veterinary use. All information provided is for educational and scientific reference only and has not been evaluated by the FDA or any medical regulatory body.