Prostamax (20mg)
$55.00 $33.00
Prostamax Product Information
Our Prostamax is a high-purity, synthetic peptide available in a 20mg size. Provided as a lyophilized powder with a certified purity of >99%, it is intended for research purposes. The SKU for this product is P-PROSTAMAX-20.
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Prostamax, or KEDP, is a synthetic tetrapeptide (Lys-Glu-Asp-Pro) that is part of the Khavinson peptides, which researchers suggest may have primary repair potential on various tissues, particularly in the prostate. Its primary mechanism of action is thought to involve influencing the structural dynamics of chromatin, the complex of DNA and proteins in cells.
1. Mechanisms of Action 🧪
Prostamax is hypothesized to affect cells at a fundamental, genetic level:
Chromatin Modulation: Research suggests that Prostamax may cause structural changes in chromatin, leading to its decondensation. This action may release previously repressed genes, reactivating genetic activities that diminish with age.
Gene Activation: The peptide is believed to increase the frequency of sister chromatid exchanges (SCE) and the number of Ag-positive nucleolus organizer regions (NORs), which may indicate enhanced chromosomal exchange and changes in ribosomal RNA gene activity.
Reducing Inflammation: In prostate tissue models, Prostamax is suggested to play a role in reducing inflammation and preventing sclerotic and atrophic processes.
Antioxidant: It is also theorized to reduce inflammation and oxidative stress.
2. Research and Clinical Studies 🔬
Cellular Aging and Genetic Modulation
Chromatin Structure: A study on lymphocytes found that Prostamax appeared to cause a relaxation of chromatin structure, changing it from a 30-nm-thick fiber to a 10-nm filament. This was associated with a decrease in denaturation temperatures, suggesting a decondensation action.
Gene Expression: In aged cells, Prostamax appeared to increase the frequency of sister chromatid exchanges by over 100% and the frequency of Ag-positive NORs by nearly 300%. This may indicate the activation of previously repressed genes.
Prostate Gland Health
Reparative Processes: In a study using prostatic gland tissue cultures from young and aged murine models, Prostamax appeared to stimulate reparative processes, suggesting a role in tissue repair, especially during aging.
Chronic Prostatitis: A study on murine models of chronic aseptic prostatitis suggested that Prostamax might reduce the intensity of chronic inflammation, including swelling and lymphoid infiltration. It also appeared to curtail the development of sclerotic and atrophic processes in the prostate.
3. Product Information 🧬
Molecular Formula: C20H33N5O9
Molecular Weight: 487.5 g/mol
Sequence: Lys-Glu-Asp-Pro
Other known titles: KEDP, SCHEMBL6660498
Important Notice: Prostamax peptide is available for research and laboratory purposes only. It is not intended for human or veterinary use. All information provided is for educational and scientific reference only and has not been evaluated by the FDA or any medical regulatory body.