Sermorelin & Ipamorelin Blend (10mg)
$55.00 $40.00
Sermorelin and Ipamorelin Product Information
This product is a 10mg blend of two high-purity peptides: Sermorelin (5mg) and Ipamorelin (5mg). It is provided in a lyophilized powder form with a certified purity of >99%, making it suitable for research applications. The SKU is P-SERMIPAM-10.
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Sermorelin and Ipamorelin are both synthetic peptides that are being researched for their potential to increase growth hormone (GH) levels. When blended, they may act synergistically, as they target different pathways to achieve a similar outcome. Sermorelin acts on the growth hormone-releasing hormone (GHRH) receptors, while Ipamorelin acts on the ghrelin receptors.
1. Mechanisms of Action 🧪
The blend's potential is based on the distinct yet complementary actions of each peptide:
Sermorelin: A 29-amino-acid peptide that mimics GHRH. It binds to GHRH receptors on the pituitary gland, which is believed to stimulate the intermittent, natural secretion of GH. This action also leads to a subsequent increase in insulin-like growth factor-1 (IGF-1), an anabolic agent.
Ipamorelin: A 5-amino-acid peptide that acts as a growth hormone secretagogue (GHS). It is thought to mimic the hunger hormone ghrelin and selectively target the ghrelin receptors (GHS-R1a) in the anterior pituitary gland.
Synergistic Effect: Because Sermorelin and Ipamorelin act on different receptors, their combined use may lead to a greater GH response than either peptide alone. Sermorelin may provide an immediate GH surge, while Ipamorelin's longer half-life (approximately 2 hours) may prolong the effect.
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2. Research and Clinical Studies 🔬
While there are no available clinical studies on the specific blend of Sermorelin & Ipamorelin, research on the individual peptides highlights their potential actions.
Growth Hormone & Lean Mass
Growth Hormone: Sermorelin has been suggested to increase average GH levels by 82% to 107%, which appeared to last for several hours. Ipamorelin has been associated with a potential increase in GH levels exceeding 6000% in research settings, a notably higher but possibly shorter-acting effect.
Lean Mass: Sermorelin has been suggested to increase lean body mass by an average of 2.78 lbs (1.26 kg) without affecting fat mass. Ipamorelin is also associated with an increase in lean mass, but its action on ghrelin receptors may lead to an increased appetite, which can result in weight gain. One study on Ipamorelin indicated a weight increase of roughly 17%.
Bone Mineralization
Bone Density: Studies on Ipamorelin suggest it may increase bone mineral content in the tibia and vertebrae, as evidenced by DEXA scans. This effect is thought to be related to its potential role in increasing lean mass and total weight.
3. Product Information 🧬
PeptideMolecular FormulaMolecular WeightOther Known TitlesSermorelinC149H246N44O42S3357.93 g/molGRF 1-29IpamorelinC38H49N9O5771.86 g/molNNC 26-0161
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Important Notice: Sermorelin & Ipamorelin blend is available for research and laboratory purposes only. It is not intended for human or veterinary use. All information provided is for educational and scientific reference only and has not been evaluated by the FDA or any medical regulatory body.