SNAP-8 (200mg)
$115.00 $106.00
SNAP-8 Product Information
Our SNAP-8 is a high-purity, synthetic peptide available in a 200mg size. Provided as a lyophilized powder with a certified purity of >99%, it is intended for research purposes. The SKU for this product is SNAP-8.
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SNAP-8 peptide is a synthetic octapeptide being researched for its potential to reduce the appearance of wrinkles and expression lines. It is designed to act as a modulator of neurotransmission by competing with the SNAP-25 protein, a key component in the release of neurotransmitters that trigger muscle contractions.
1. Mechanisms of Action 🧪
The potential actions of SNAP-8 are hypothesized to occur at the neuromuscular junction:
Competing with SNAP-25: SNAP-8 is designed to compete with the native SNAP-25 protein to bind with vesicle-associated membrane proteins, such as Synaptotagmin 1 (Syt1).
SNARE Complex Destabilization: The binding of SNAP-8 is thought to destabilize the formation of the SNARE complex. This protein complex is essential for the fusion of neurotransmitter-containing vesicles with the cell membrane.
Inhibiting Acetylcholine Release: By disrupting the SNARE complex, SNAP-8 may inhibit the release of acetylcholine, a neurotransmitter that causes muscle contractions.
Reducing Muscle Contractions: The reduced release of acetylcholine is believed to lead to decreased muscle activity, which in turn may reduce the formation and depth of wrinkles and fine lines.
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2. Research and Clinical Studies 🔬
Skin Wrinkling and Topography
Wrinkle Reduction: A double-blind, randomized clinical trial showed that a SNAP-8 serum appeared to cause a notable reduction in lines within 15 minutes of exposure and a significant overall skin improvement after 12 weeks.
Clinical Efficacy: Research on Argireline, a similar peptide, indicated a 49% reduction in lines and decreased skin roughness after four weeks, which may suggest a parallel potential for SNAP-8.
Texture and Depth: A study using a 10% peptide oil-in-water emulsion reported a ~30% reduction in the depth and appearance of wrinkles over a month-long routine exposure.
Neurotransmission
Glutamate Reduction: One study suggested that SNAP-8 appeared to reduce the release of the amino acid glutamate by almost 43%, further indicating its potential to modulate neurotransmitter release.
3. Product Information 🧬
Molecular Formula: C41H70N16O6S
Molecular Weight: 1075.16 g/mol
Other Known Titles: SNAP-8 (Acetyl Glutamyl Heptapeptide-3), Synaptosomal-associated protein 8, Acetyl octapeptide-3
Important Notice: SNAP-8 peptide is available for research and laboratory purposes only. It is not intended for human or veterinary use. All information provided is for educational and scientific reference only and has not been evaluated by the FDA or any medical regulatory body.