Thymagen (20mg)
$88.00 $78.00
Thymagen Product Information
Our Thymagen is a high-purity, synthetic peptide available in a 20mg size. Provided as a lyophilized powder with a certified purity of >99%, it is intended for research purposes. The SKU for this product is P-THYMAGEN-20.
Pricing and Discounts
Price: $78.00 per unit.
5-8 units: A 5% discount is applied, with a price of $74.10 per unit.
9+ units: A 10% discount is applied, with a price of $70.20 per unit.
We also offer FREE shipping on all orders over $200.
Thymagen (also known as EW or Oglufanide) is a synthetic dipeptide being researched for its potential as an immunomodulator. Classified as a Khavinson peptide, it is a synthetic analog of the thymus-derived protein thymalin. Research suggests it may interact with the immune system by influencing immune cells, modulating inflammatory responses, and potentially enhancing the body's natural defenses against infections and other conditions.
1. Mechanisms of Action 🧪
Thymagen's potential actions are centered on modulating various components of the immune system:
Modulating Cyclic Nucleotides: The peptide may influence the ratio of cyclic adenosine monophosphate (cAMP) to cyclic guanosine monophosphate (cGMP), particularly in lymphocytes, which are important signaling molecules in immune responses. This action is thought to help balance the immune system, especially in models of hypersensitivity and anaphylaxis.
Enhancing Non-specific Resistance: In models of bacterial infection, Thymagen appeared to enhance the non-specific resistance of murine models, which may have contributed to a reduced spread and facilitated the elimination of infective agents.
T-lymphocyte Differentiation: The peptide is being researched for its potential role in regulating immunological processes, including T-lymphocyte differentiation and mitigating secondary immunodeficiency.
2. Research and Clinical Studies 🔬
Immune System Regulation
Bacterial Infections: In murine models of Yersinia enterocolitica infection, Thymagen appeared to reduce the spread of the infection and enhance non-specific resistance.
Fungal Infections: Studies in murine models with secondary immunodeficiency and candidiasis suggested that Thymagen may help mitigate the severity of the infection by possibly activating the immunocompetent system, including the thymus.
Autoimmune Conditions: In models of autoimmune conditions, Thymagen appeared to modulate certain immune responses, which may reduce potential secondary immune deficits.
Other Research Areas
Cardiac Cells: Thymagen has been researched for its potential in addressing various types of arrhythmias in murine models, with findings suggesting an anti-ischemic action.
Tumor Cells: In studies on murine models exposed to carcinogens or radiation, Thymagen appeared to reduce the occurrence and multiplicity of tumor cells. In one study, it was associated with an apparently longer lifespan and a lower incidence of both malignant and benign tumors.
Solid Tumors: Research on subjects with solid tumors suggested that Thymagen may aid in restoring structural and functional parameters of cellular immunity before manual excision, potentially reducing complications and shortening recovery time.
3. Product Information 🧬
Molecular Formula: C16H19N3O5
Molecular Weight: 333.3 g/mol
Sequence: Glu-Trp
Other Known Titles: Oglufanide, Thymogen
Important Notice: Thymagen peptide is available for research and laboratory purposes only. It is not intended for human or veterinary use. All information provided is for educational and scientific reference only and has not been evaluated by the FDA or any medical regulatory body.